Proposal-determine if the cell cycle proteins are expressed at Essay

Proposal-determine if the cell cycle proteins are expressed at different stages of nurse cell development in Trichinella spires infected muscle - Essay Example The life cycle of Trichinella begins with larvae being ingested raw or undercooked, pork meat. The larvae attach and bury themselves in the intestinal mucosa developing into adults in the small intestines. The adults in the intestinal mucosa mate producing more larvae. A single female can produce up to 1500 over a period of 1 to for weeks. The produced larvae then enter the lymph and mesenteric veins traveling throughout the body eventually attaching itself as a cyst in the striated muscle. The cyst helps the Trichinella species to survive the host’s immune system. The larva may remain viable for up to 25 years in humans. The viable cysts when ingested by a new host they become viable again beginning the cycle. The nematodes of genus Trichinella infect a wide range of mammal’s reptiles and birds. The parasite usually alternate between the enteric and skeletal muscle stages within their hosts. The eleven known genotypes are made up of two categories. The first is the species that encapsulation occurs and that one that no encapsulation occurs. (Zarlenga et al. 2004). T spirally is the most common cause of human infections, and much of the proposal will discuss this species. The T spirally usually inhabits the host muscle cells and become encapsulated. The Trichinella species is found in a broad geographic range from the tropics to the Arctic. The encapsulated species shows more adaptations to colder climates as compared to the encapsulated species. The major hosts of Trichinella species are sylvatic swine and domestic swine. The synanthropic group of animals such as rat’s cats, dogs, and carnivore also from the host to the Trichinella species. The high infections to swine mean that Trichinella species spread to most continents thus showing a cosmopolitan distribution in equatorial and temperate climates (Pozio 2001). The species has been classified into three by use of molecular phylogenetics(Blaxter et al. 1998).